Pealkiri: 

Molecular epidemiology of hepatitis A, B and C in Estonia

Autorid: Tallo T
Väljaandja/tellija: Karolinska Institutet
Märksõnad: A-hepatiit, B-hepatiit, C-hepatiit, epidemioloogia, epidemioloogilised uuringud, nakkushaigused
Välja antud: 2008
Tüüp: Doktoritöö
Failid:
Nimi SuurusFormaat
Tallo2008.pdf1.73 MBAdobe PDF
Alamvaldkonnad:Nakkushaigused
Kirjeldus: The present investigation was undertaken to study the genetic variability of HAV, HBV and HCV in Estonia. This was approached through the following specific aims:
To determine the genotypes of HAV strains from Estonia and their genetic relatedness to HAV strains isolated from other geographic areas and to investigate the molecular epidemiology of a community-wide outbreak of hepatitis A in Estonia.
To determine the genotypes and subtypes of HBV strains isolated from Estonia and from different regions of the former USSR and to investigate their genetic relatedness.
To characterize the complete genomes of HBV strains from Estonia and different regions of the former USSR to classify them into subgenotypes and to investigate HBV strains with identical small S-genes.
To determine the subtypes of HCV strains circulating in Estonia during the last decade and to characterize their relatedness to HCV strains from other parts of the world.